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Student conference

MiR-X May Be Protective in Ischemic-Reperfusion

By Amber Pollock

EMS300 Student Conference 2026

Slide 1: MiR-X may be protective in ischemic-reperfusion. A full description follows.

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Summary

The slide deck presents research on the protective effects of MiR-X in ischemic-reperfusion injury within mouse models of acute kidney injury (AKI). It highlights the increasing incidence and limited treatment options for AKI, and investigates the impact of a MiR-X mimic on renal injury and fibrosis. Key findings indicate that MiR-X over-expression reduces pro-inflammatory gene expression and renal injury, although fibrosis reduction was only trend-based. Recommendations include further studies with larger sample sizes and bilateral IRI models to validate these findings.

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